CIG
You are here:  Home arrow Organisms arrow Starlet anemone
 

Starlet anemone (Nematostella vectensis

N. vectensis genome facts:
sequenced 2004-5; annotated 2006
475 million base pairs
27,000 genes

Image
Nematostella feeding series

 

↓ general and genome resource links ↓

 

Nematostella vectensis, the starlet sea anemone, is a burrowing animal found in estuarine environments in the coastal U.K. and North America. Sea anemones belong to the phylum Cnidaria, a group characterized by a sac-like body plan with two germ layers (the ectoderm and the endoderm), radial symmetry and stinging cells called nematocytes. Nematostella is special among the cnidarians because is possesses swimming congregations of nematocytes called nematosomes, that are found throughout the gut and in the hollows of the tentacles and are delivered in the egg sacs to protect the developing embryos.

The Nematostella adult is a sedentary polyp that feeds on small zooplankton using its tentacles. Food enters the gut through the pharynx and is digested externally in the body cavity, which is lined by infoldings of the endoderm, the mesenteries. Male and female animals spawn to produce sperm and eggs. Upon fertilization, the zygote develops into a blastula that gastrulates by invagination and ingression and then results in a swimming larva called the planula. The planula then settles and transforms into a juvenile polyp. Unlike its more glamorous cousins, the jellyfish, anemones don’t have a swimming medusa stage in their life history.

Anemones and corals together make up the class Anthozoa that diverged away from other classes (Scyphozoa, Hydrozoa and Cubozoa) early in the evolution of the cnidarians. This position within the Cnidaria makes the study of anthozoans essential to understanding the common ancestor of cnidarians, and through that, the ancestor cnidarians share with all other true metazoans (all multicellular animals except for sponges).

Juvenile polyp
Juvenile polyp, stained to show nuclei
Nematostella has become an invaluable system for the study of development of cnidarians because of the ease with which it can be cultivated in the laboratory. The animals can be spawned at will using stimuli such as food, light and temperature and the developmental stages studied within a reasonable time period (5 days from fertilization to juvenile polyp). This convenience as a lab rat and its modest genome size (475 Mb) made Nematostella an excellent candidate for genome sequencing by the JGI.


Researchers are using Nematostella to understand the early evolution of animals by comparing the embryonic development of this organism to what we know about how model organisms such as flies, nematodes and mice (bilaterians) develop at the molecular level. Studies on genes involved in bilateral symmetry and mesoderm specification have revealed that though cnidarians don’t possess these morphological characters in general, they do express the genes involved in establishing these characters in bilaterians. Research on genes involved in neural specification and patterning in Nematostella are giving us clues about what the first animal nervous system looked like. These data along with further inquiries into the functions of these genes in cnidarians promise to unravel the mysterious origins of many animal tissues, organs and processes. 
 


CIG faculty who study me:

Dan Rokhsar


Related research projects: